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Mpox has been a public health problem in parts of Africa for decades

New Delhi:
The World Health Organization has declared that an outbreak of mpox, a viral infection that spreads through close contact, represents a global health emergency for the second time in two years. Mpox causes flu-like symptoms and pus-filled lesions.

Here’s your 10-point cheat sheet to this big story

  1. While usually mild, mpox can kill. Children, pregnant women and people with weakened immune systems, such as those with HIV, are all at higher risk of complications. The WHO declared the recent outbreak of the disease a public health emergency after a new offshoot of the mpox virus, first identified in Democratic Republic of Congo, began spreading to other neighbouring countries.

  2. Two years ago, the WHO declared mpox was an emergency when a form of the disease, ‘clade IIb’, began to spread globally, largely among men who have sex with men. That outbreak was brought under control after behaviour change and safe sex practices, plus vaccines, helped people at risk protect themselves in many countries.

  3. But mpox has been a public health problem in parts of Africa for decades. The first ever human case was in Congo in 1970, and it has had outbreaks ever since. The current outbreak, Congo’s worst ever, has seen 27,000 cases and more than 1,100 deaths since January 2023, largely among children.

  4. Two strains of mpox are now spreading in Congo – the endemic form of the virus, ‘clade I’, and a new offshoot called ‘clade Ib’, with the term ‘clade’ referring to a form of the virus. The new offshoot has now moved from eastern Congo to Rwanda, Uganda, Burundi and Kenya.

  5. Sweden reported the first case of the new form, ‘clade Ib’, outside Africa on Thursday. A WHO spokesperson said the case reiterated the need for partnership, and the agency continues to advise against travel restrictions to stop the spread of mpox. Pakistan on Friday also confirmed a case of the mpox virus in a patient who had returned from a Gulf country, though it was unclear whether it was of the new variant or of the clade that has been spreading globally since 2022.

  6. But in 2022, a WHO appeal for $34 million to fight mpox got no take-up from donors, and there was huge inequity in who had access to vaccine doses. African countries had no access to the two shots used in the global outbreak, made by Bavarian Nordic and KM Biologics.

  7. Two years later that remains the case, although there are efforts to change that, the WHO said on Wednesday as it appealed for dose donations from countries with stockpiles. Africa CDC said it has a plan to secure doses, without elaborating further, but stocks are currently limited.

  8. Fatality rates vary, and depend heavily on the healthcare available to the sickest patients. In Congo in this outbreak, the rate across both ‘clade I’ and ‘clade Ib’ has been around 4 per cent. ‘Clade II’, which spread globally, was much less deadly.

  9. However, mpox is not COVID-19. There are tools that are proven to work to stop the spread and help those at risk, and it does not spread as easily. The challenge now, which the emergency declarations aim to highlight, is making sure those tools reach those who need them most, in Congo and neighbouring countries.

With inputs from Reuters

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The DRC is made up of 26 provinces and has a population of around 100 million. (File)

DR Congo:

An mpox outbreak in the Democratic Republic of Congo has killed 548 people since the start of the year, with all provinces affected by the virus, the health minister said on Thursday in a statement.

The World Health Organization (WHO) on Wednesday declared the mpox surge in Africa a global public health emergency, worried by the rise in cases in DRC and the spread to nearby countries.

“According to the latest epidemiological report, our country has recorded 15,664 potential cases and 548 deaths since the beginning of the year,” Health Minister Samuel-Roger Kamba said in a separate video message seen by AFP on Thursday.

The DRC is made up of 26 provinces and has a population of around 100 million.

The most affected provinces are South Kivu, North Kivu, Tshopo, Equateur, North Ubangi, Tshuapa, Mongala and Sankuru, Kamba said.

The UN health agency’s decision came the day after the African Union’s health watchdog declared its own public health emergency over the growing outbreak.

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)

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Africa mpox resurgence, with deadlier and more transmissable strain, fuels alarm https://artifexnews.net/article68496646-ece/ Wed, 07 Aug 2024 11:41:26 +0000 https://artifexnews.net/article68496646-ece/ Read More “Africa mpox resurgence, with deadlier and more transmissable strain, fuels alarm” »

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Two years after a global outbreak, fears are rife that a new strain of mpox — previously known as monkeypox — identified in DR Congo and now also in several neighbouring countries could further spread.

Deadlier and more transmissible than previous forms, the mpox strain surging in the Democratic Republic of Congo (DRC) since September, known as the Clade Ib subclade, is spread person-to-person.

The World Health Organization (WHO) said on Sunday it was considering convening an expert committee to advise on whether to declare an international emergency, as it did during the global mpox outbreak in 2022.

The Clade Ib strain causes skin rashes across the whole body, unlike other strains where lesions and rashes are usually limited to the mouth, face and genitals.

The African Union health agency, Africa CDC, registered 14,479 confirmed and suspected cases of the strain and 455 deaths in DRC as of August 3, representing a mortality rate of around three percent.

But researchers in the vast Central African nation say the mortality rate from the strain can be as much as 10 percent among children.

The Congolese government acknowledged last month an “exponential increase” in cases.

“The disease has been seen in the displacement camps around Goma in North Kivu where the extreme population density makes the situation very critical,” Louis Albert Massing, medical coordinator for Doctors Without Borders in DRC said.

“The risks of explosion are real given the enormous population movements” in the conflict-ridden region, which borders several countries, he added.

Already, the Clade Ib strain has jumped national borders — in the last two weeks, cases have been reported in Uganda, Burundi, Rwanda and Kenya, Rosamund Lewis, the WHO’s technical lead for mpox, told AFP.

‘Raging’

Authorities in the four countries have confirmed mpox cases — Burundi in particular has reported 127 cases — without specifying the strain.

The eight-member East African Community (EAC) has urged governments to educate their citizens on how to protect themselves and prevent the spread of the disease.

Lewis, from the WHO, said it was the first time that the four countries lying to the east of DRC had reported mpox cases.

“Rwanda, Burundi, Uganda are countries that don’t have this disease in an endemic way… that means it’s an extension of the outbreak which is raging in the DRC and in Central Africa generally,” she said.

Africa CDC has also reported 35 suspected and confirmed cases, including two deaths, in Cameroon, 146 cases, including one death, in Congo Brazzaville, 227 cases in the Central African Republic, 24 in Nigeria, five in Liberia and four cases in Ghana.

In West Africa, Ivory Coast recently reported six confirmed non-fatal cases, five of which were in the economic capital Abidjan, without specifying the strain.

Detection capacity

Mpox was first discovered in humans in 1970 in the DRC, then called Zaire. It has since been mainly limited to certain West and Central African nations. Humans mainly catch it from infected animals, such as when eating bushmeat.

In May 2022, mpox infections surged worldwide, mostly affecting gay and bisexual men. That spike was driven by a new subtype, dubbed Clade II, which took over from Clade I. Around 140 people died out of about 90,000 cases across 111 countries.

The outbreak is “still raging”, Lewis said, including in South Africa, which has seen 24 cases, three of which were fatal, but she added it was “controlled” and spreading less.

Mpox remains a global health threat, WHO chief Tedros Adhanom Ghebreyesus warned in early July.

Countries are now able to detect cases, Lewis said, pointing to a system of surveillance, laboratories and communication with affected areas. It is hard to know if there has been “a substantial rise” in cases, or whether “it’s just a matter of increased awareness”, said Maria Van Kerkhove, the WHO’s epidemic and pandemic preparedness and prevention director, who confirmed concern over the Clade Ib strain.

“There are some vaccines that are licensed that can be used for mpox,” she said.

Negotiations between the WHO and affected countries are under way to authorise the use of one, Lewis said.



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