Sumatran orangutan named Rakus seen two months after wound self-treatment using a medicinal plant, in Indonesia.
| Photo Credit: Reuters

In the May 2, 2024, issue of the journal Nature, an article titled: ‘Active self-treatment of a facial wound with a biologically active plant by a male Sumatran orangutan’, Laumer et al. report on how this primate in Indonesia treats a wound on its face by making a paste of the local plant Fibraurea tinctoria, and applied it to the wound. A 2012 publication by Matt Kaplan in Nature, titled: ‘Neanderthals ate their greens’, analysed the dental plaque of some Neanderthals from Northern Spain, and found that they used plants such as yarrow and chamomile, to rid themselves of infections and for their general health.

Several such plants have been used by people across the world in traditional medicine, to overcome infections and for general health. The comprehensive review by R Raman and S Kandula in (Resonance, 245-253, March 2008) points out that the ecologist D H Janzen from the University of Pennsylvania, coined the term ‘zoopharmacognosy’, and was the first one to compile a list of animals that self-medicate by ingesting or topically applying specific plants, soil and insects. Besides offering essential molecules for metabolism and growth, these also offer disease treatment and protection from parasites. (‘zoo’ refers to animals, and pharmacognosy to the study of drugs and tonics for health). Dr E M Costa-Neto of Bahia, Brazil, in “Environmental Science, Biology” in 2012 titled: ‘Zoopharmacognosy: the self-medication behaviour of animals’, as also Joel Shurkin from Baltimore, in the Proceedings of the National Academy of Sciences have listed several plants and their roots, leaves and fruits that apes, monkeys, reindeer, bears and some birds (starlings) eat to stay healthy. Dogs medicate themselves by chewing grass and vomiting it to get rid of infections in the stomach. Pregnant lemurs nibble on tamarind leaves to aid milk production, and pregnant elephants in Kenya eat the leaves of some plants of the Boraginaceae family to induce delivery. The Roman natural historian Pliny pointed out 2,000 years ago that many animals had made medical discoveries from certain plants that they eat, which became useful knowledge for indigenous people. Many of these medicinal plants have been known for over 3,000 years in Africa, Egypt, Middle East, India and China, and are still used today.

Traditional medicines

The medicinal plant Fibrourea tinctoria that the Sumatran orangutan used for wound healing contains the anti-inflammatory molecule berberine. Called ‘Akar Kunyi’ locally, the plant is used in the traditional medical system there. And in the southern subtropical regions, its equivalent is called Oleander and is used as a curative for jaundice. The shrub aloe vera, which is found in India (where it is called ‘gwar patta’ in Hindi and ‘katrazhai’ in Tamil) and many parts of Asia and Africa, has antimicrobial, anti-inflammatory and wound healing properties.

Several civilizations have recorded and used natural systems of medicine for thousands of years. China has had the Zhongyi system for the past 5,000 years, Arabia for 4,000 years and the Indian Ayurvedic system for 5,000 years. They all use various plants, fruits and roots such as Rauwolfina serpentina (sarpagandha in Hindi), and holy basil (tulsi), aloe vera, wild garlic, onion, oregano, artichokes, camphor, coconut and castor oil. The natural products-based ‘Chyavana Prasha’ is popular in India; a formula for it is recorded in the Charaka Samhita from around 700 BC. We now look forward to biochemists and drug companies for new natural product molecules.